Ablation of Neurogenesis Attenuates Recovery of Motor Function after Focal Cerebral Ischemia in Middle-Aged Mice

Depletion of neurogenesis worsens functional outcome in young-adult mice after focal cerebral ischemia, but whether a similar effect occurs in older mice is unknown. Using middle-aged (12-month-old) transgenic (DCX-TK((+))) mice that express herpes simplex virus thymidine kinase (HSV-TK) under contr...

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Detalles Bibliográficos
Autores principales: Sun, Fen, Wang, Xiaomei, Mao, XiaoOu, Xie, Lin, Jin, Kunlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482223/
https://www.ncbi.nlm.nih.gov/pubmed/23110048
http://dx.doi.org/10.1371/journal.pone.0046326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482223/
https://www.ncbi.nlm.nih.gov/pubmed/23110048
http://dx.doi.org/10.1371/journal.pone.0046326

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