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Structure-based prediction of protein-protein interactions on a genome-wide scale
The genome-wide identification of pairs of interacting proteins is an important step in the elucidation of cell regulatory mechanisms(1,2). Much of our current knowledge derives from high-throughput techniques such as yeast two hybrid and affinity purification(3), as well as from manual curation of...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482288/ https://www.ncbi.nlm.nih.gov/pubmed/23023127 http://dx.doi.org/10.1038/nature11503 |