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Structure of the agonist-bound neurotensin receptor

Neurotensin (NT) is a 13 amino acid peptide that functions as both a neurotransmitter and a hormone through activation of the neurotensin receptor NTS1, a G protein-coupled receptor (GPCR). In the brain, NT modulates activity of dopaminergic systems, opioid-independent analgesia, and the inhibition...

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Detalles Bibliográficos
Autores principales: White, Jim F., Noinaj, Nicholas, Shibata, Yoko, Love, James, Kloss, Brian, Xu, Feng, Gvozdenovic-Jeremic, Jelena, Shah, Priyanka, Shiloach, Joseph, Tate, Christopher G., Grisshammer, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482300/
https://www.ncbi.nlm.nih.gov/pubmed/23051748
http://dx.doi.org/10.1038/nature11558