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A Two-Step Mechanism for the Activation of Actinorhodin Export and Resistance in Streptomyces coelicolor
Many microorganisms produce secondary metabolites that have antibiotic activity. To avoid self-inhibition, the producing cells often encode cognate export and/or resistance mechanisms in the biosynthetic gene clusters for these molecules. Actinorhodin is a blue-pigmented antibiotic produced by Strep...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Microbiology
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482498/ https://www.ncbi.nlm.nih.gov/pubmed/23073761 http://dx.doi.org/10.1128/mBio.00191-12 |