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Short hairpin RNA targeting 2B gene of coxsackievirus B3 exhibits potential antiviral effects both in vitro and in vivo

BACKGROUND: Coxsackievirus B3 is an important infectious agent of viral myocarditis, pancreatitis and aseptic meningitis, but there are no specific antiviral therapeutic reagents in clinical use. RNA interference-based technology has been developed to prevent the viral infection. METHODS: To evaluat...

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Detalles Bibliográficos
Autores principales: Yao, Hailan, Zhang, Yangde, He, Feng, Wang, Caihong, Xiao, Zonghui, Zou, Jizhen, Wang, Fang, Liu, Zhewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482581/
https://www.ncbi.nlm.nih.gov/pubmed/22863145
http://dx.doi.org/10.1186/1471-2334-12-177