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Appraising the performance of genotyping tools in the prediction of coreceptor tropism in HIV-1 subtype C viruses
BACKGROUND: In human immunodeficiency virus type 1 (HIV-1) infection, transmitted viruses generally use the CCR5 chemokine receptor as a coreceptor for host cell entry. In more than 50% of subtype B infections, a switch in coreceptor tropism from CCR5- to CXCR4-use occurs during disease progression....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482586/ https://www.ncbi.nlm.nih.gov/pubmed/22938574 http://dx.doi.org/10.1186/1471-2334-12-203 |