Appraising the performance of genotyping tools in the prediction of coreceptor tropism in HIV-1 subtype C viruses

BACKGROUND: In human immunodeficiency virus type 1 (HIV-1) infection, transmitted viruses generally use the CCR5 chemokine receptor as a coreceptor for host cell entry. In more than 50% of subtype B infections, a switch in coreceptor tropism from CCR5- to CXCR4-use occurs during disease progression....

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Detalles Bibliográficos
Autores principales: Crous, Saleema, Shrestha, Ram Krishna, Travers, Simon A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482586/
https://www.ncbi.nlm.nih.gov/pubmed/22938574
http://dx.doi.org/10.1186/1471-2334-12-203

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