Vitamin K1 enhances sorafenib-induced growth inhibition and apoptosis of human malignant glioma cells by blocking the Raf/MEK/ERK pathway

BACKGROUND: The combined effects of anticancer drugs with nutritional factors against tumor cells have been reported previously. This study characterized the efficacy and possible mechanisms of the combination of sorafenib and vitamin K1 (VK1) on glioma cell lines. METHODS: We examined the effects o...

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Detalles Bibliográficos
Autores principales: Du, Wei, Zhou, Jing-ru, Wang, Dong-liang, Gong, Kai, Zhang, Qing-jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482596/
https://www.ncbi.nlm.nih.gov/pubmed/22520038
http://dx.doi.org/10.1186/1477-7819-10-60

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482596/
https://www.ncbi.nlm.nih.gov/pubmed/22520038
http://dx.doi.org/10.1186/1477-7819-10-60

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