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Neutron diffraction studies of the interaction between amphotericin B and lipid-sterol model membranes

Over the last 50 years or so, amphotericin has been widely employed in treating life-threatening systemic fungal infections. Its usefulness in the clinic, however, has always been circumscribed by its dose-limiting side-effects, and it is also now compromised by an increasing incidence of pathogen r...

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Detalles Bibliográficos
Autores principales: Foglia, Fabrizia, Lawrence, M. Jayne, Demė, Bruno, Fragneto, Giovanna, Barlow, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482691/
https://www.ncbi.nlm.nih.gov/pubmed/23110248
http://dx.doi.org/10.1038/srep00778