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Inhibition of activin/nodal signalling is necessary for pancreatic differentiation of human pluripotent stem cells

AIMS/HYPOTHESIS: Human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hIPSCs) offer unique opportunities for regenerative medicine and for the study of mammalian development. However, developing methods to differentiate hESCs/hIPSCs into specific cell types following a natura...

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Detalles Bibliográficos
Autores principales: Cho, C. H.-H., Hannan, N. R.-F., Docherty, F. M., Docherty, H. M., Joåo Lima, M., Trotter, M. W. B., Docherty, K., Vallier, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483105/
https://www.ncbi.nlm.nih.gov/pubmed/23011350
http://dx.doi.org/10.1007/s00125-012-2687-x