Charge movement in gating-locked HCN channels reveals weak coupling of voltage sensors and gate

HCN (hyperpolarization-activated cyclic nucleotide gated) pacemaker channels have an architecture similar to that of voltage-gated K(+) channels, but they open with the opposite voltage dependence. HCN channels use essentially the same positively charged voltage sensors and intracellular activation...

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Detalles Bibliográficos
Autores principales: Ryu, Sujung, Yellen, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483112/
https://www.ncbi.nlm.nih.gov/pubmed/23071265
http://dx.doi.org/10.1085/jgp.201210850

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483112/
https://www.ncbi.nlm.nih.gov/pubmed/23071265
http://dx.doi.org/10.1085/jgp.201210850

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