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Charge movement in gating-locked HCN channels reveals weak coupling of voltage sensors and gate
HCN (hyperpolarization-activated cyclic nucleotide gated) pacemaker channels have an architecture similar to that of voltage-gated K(+) channels, but they open with the opposite voltage dependence. HCN channels use essentially the same positively charged voltage sensors and intracellular activation...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483112/ https://www.ncbi.nlm.nih.gov/pubmed/23071265 http://dx.doi.org/10.1085/jgp.201210850 |