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Distinct properties of Ca(2+)–calmodulin binding to N- and C-terminal regulatory regions of the TRPV1 channel

Transient receptor potential (TRP) vanilloid 1 (TRPV1) is a molecular pain receptor belonging to the TRP superfamily of nonselective cation channels. As a polymodal receptor, TRPV1 responds to heat and a wide range of chemical stimuli. The influx of calcium after channel activation serves as a negat...

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Detalles Bibliográficos
Autores principales: Lau, Sze-Yi, Procko, Erik, Gaudet, Rachelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483115/
https://www.ncbi.nlm.nih.gov/pubmed/23109716
http://dx.doi.org/10.1085/jgp.201210810