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Distinct properties of Ca(2+)–calmodulin binding to N- and C-terminal regulatory regions of the TRPV1 channel
Transient receptor potential (TRP) vanilloid 1 (TRPV1) is a molecular pain receptor belonging to the TRP superfamily of nonselective cation channels. As a polymodal receptor, TRPV1 responds to heat and a wide range of chemical stimuli. The influx of calcium after channel activation serves as a negat...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483115/ https://www.ncbi.nlm.nih.gov/pubmed/23109716 http://dx.doi.org/10.1085/jgp.201210810 |