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Modeling-independent elucidation of inactivation pathways in recombinant and native A-type Kv channels

A-type voltage-gated K(+) (Kv) channels self-regulate their activity by inactivating directly from the open state (open-state inactivation [OSI]) or by inactivating before they open (closed-state inactivation [CSI]). To determine the inactivation pathways, it is often necessary to apply several puls...

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Detalles Bibliográficos
Autores principales: Fineberg, Jeffrey D., Ritter, David M., Covarrubias, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483116/
https://www.ncbi.nlm.nih.gov/pubmed/23109714
http://dx.doi.org/10.1085/jgp.201210869