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Basis for allosteric open-state stabilization of voltage-gated potassium channels by intracellular cations
The open state of voltage-gated potassium (Kv) channels is associated with an increased stability relative to the pre-open closed states and is reflected by a slowing of OFF gating currents after channel opening. The basis for this stabilization is usually assigned to intrinsic structural features o...
Autores principales: | Goodchild, Samuel J., Xu, Hongjian, Es-Salah-Lamoureux, Zeineb, Ahern, Christopher A., Fedida, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483119/ https://www.ncbi.nlm.nih.gov/pubmed/23071269 http://dx.doi.org/10.1085/jgp.201210823 |
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