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Local axonal function of STAT3 rescues axon degeneration in the pmn model of motoneuron disease

Axonal maintenance, plasticity, and regeneration are influenced by signals from neighboring cells, in particular Schwann cells of the peripheral nervous system. Schwann cells produce neurotrophic factors, but the mechanisms by which ciliary neurotrophic factor (CNTF) and other neurotrophic molecules...

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Detalles Bibliográficos
Autores principales: Selvaraj, Bhuvaneish Thangaraj, Frank, Nicolas, Bender, Florian L.P., Asan, Esther, Sendtner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483126/
https://www.ncbi.nlm.nih.gov/pubmed/23109669
http://dx.doi.org/10.1083/jcb.201203109