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Hypertrophic cardiomyopathy: Translating cellular cross talk into therapeutics

Hypertrophic cardiomyopathy (HCM) is a common inherited heart disease with serious adverse outcomes, including heart failure, arrhythmias, and sudden cardiac death. The discovery that mutations in sarcomere protein genes cause HCM has enabled the development of mouse models that recapitulate clinica...

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Detalles Bibliográficos
Autores principales: Teekakirikul, Polakit, Padera, Robert F., Seidman, J.G., Seidman, Christine E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483129/
https://www.ncbi.nlm.nih.gov/pubmed/23109667
http://dx.doi.org/10.1083/jcb.201207033