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Using force to visualize conformational activation of integrins
The development of biophysical approaches to analyze integrin–ligand binding allows us to visualize in real time the conformational changes that shift the bond affinity between low- and high-affinity states. In this issue, Chen et al. (2012. J. Cell Biol. http://dx.doi.org/jcb.201201091) use these a...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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The Rockefeller University Press
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483130/ https://www.ncbi.nlm.nih.gov/pubmed/23109668 http://dx.doi.org/10.1083/jcb.201209073 |