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Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation

Caveolin-1 (Cav1) is an essential component of caveolae whose Src kinase-dependent phosphorylation on tyrosine 14 (Y14) is associated with regulation of focal adhesion dynamics. However, the relationship between these disparate functions remains to be elucidated. Caveola biogenesis requires expressi...

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Detalles Bibliográficos
Autores principales: Joshi, Bharat, Bastiani, Michele, Strugnell, Scott S., Boscher, Cecile, Parton, Robert G., Nabi, Ivan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483133/
https://www.ncbi.nlm.nih.gov/pubmed/23091071
http://dx.doi.org/10.1083/jcb.201207089