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Phosphocaveolin-1 is a mechanotransducer that induces caveola biogenesis via Egr1 transcriptional regulation
Caveolin-1 (Cav1) is an essential component of caveolae whose Src kinase-dependent phosphorylation on tyrosine 14 (Y14) is associated with regulation of focal adhesion dynamics. However, the relationship between these disparate functions remains to be elucidated. Caveola biogenesis requires expressi...
Autores principales: | Joshi, Bharat, Bastiani, Michele, Strugnell, Scott S., Boscher, Cecile, Parton, Robert G., Nabi, Ivan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483133/ https://www.ncbi.nlm.nih.gov/pubmed/23091071 http://dx.doi.org/10.1083/jcb.201207089 |
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