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Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility

The mechanical microenvironment is known to influence single-cell migration; however, the extent to which mechanical cues affect collective migration of adherent cells is not well understood. We measured the effects of varying substrate compliance on individual cell migratory properties in an epithe...

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Detalles Bibliográficos
Autores principales: Ng, Mei Rosa, Besser, Achim, Danuser, Gaudenz, Brugge, Joan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483134/
https://www.ncbi.nlm.nih.gov/pubmed/23091067
http://dx.doi.org/10.1083/jcb.201207148