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Assessing Predictors of Changes in Protein Stability upon Mutation Using Self-Consistency
The ability to predict the effect of mutations on protein stability is important for a wide range of tasks, from protein engineering to assessing the impact of SNPs to understanding basic protein biophysics. A number of methods have been developed that make these predictions, but assessing the accur...
Autores principales: | Thiltgen, Grant, Goldstein, Richard A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483175/ https://www.ncbi.nlm.nih.gov/pubmed/23144695 http://dx.doi.org/10.1371/journal.pone.0046084 |
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