A Streamlined Method for Detecting Structural Variants in Cancer Genomes by Short Read Paired-End Sequencing

Defining the architecture of a specific cancer genome, including its structural variants, is essential for understanding tumor biology, mechanisms of oncogenesis, and for designing effective personalized therapies. Short read paired-end sequencing is currently the most sensitive method for detecting...

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Detalles Bibliográficos
Autores principales: Mijušković, Martina, Brown, Stuart M., Tang, Zuojian, Lindsay, Cory R., Efstathiadis, Efstratios, Deriano, Ludovic, Roth, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483208/
https://www.ncbi.nlm.nih.gov/pubmed/23144753
http://dx.doi.org/10.1371/journal.pone.0048314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483208/
https://www.ncbi.nlm.nih.gov/pubmed/23144753
http://dx.doi.org/10.1371/journal.pone.0048314

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