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A Streamlined Method for Detecting Structural Variants in Cancer Genomes by Short Read Paired-End Sequencing
Defining the architecture of a specific cancer genome, including its structural variants, is essential for understanding tumor biology, mechanisms of oncogenesis, and for designing effective personalized therapies. Short read paired-end sequencing is currently the most sensitive method for detecting...
Autores principales: | Mijušković, Martina, Brown, Stuart M., Tang, Zuojian, Lindsay, Cory R., Efstathiadis, Efstratios, Deriano, Ludovic, Roth, David B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483208/ https://www.ncbi.nlm.nih.gov/pubmed/23144753 http://dx.doi.org/10.1371/journal.pone.0048314 |
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