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AP-3 and Rabip4’ Coordinately Regulate Spatial Distribution of Lysosomes

The RUN and FYVE domain proteins rabip4 and rabip4’ are encoded by RUFY1 and differ in a 108 amino acid N-terminal extension in rabip4’. Their identical C terminus binds rab5 and rab4, but the function of rabip4s is incompletely understood. We here found that silencing RUFY1 gene products promoted o...

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Detalles Bibliográficos
Autores principales: Ivan, Viorica, Martinez-Sanchez, Emma, Sima, Livia E., Oorschot, Viola, Klumperman, Judith, Petrescu, Stefana M., van der Sluijs, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483219/
https://www.ncbi.nlm.nih.gov/pubmed/23144738
http://dx.doi.org/10.1371/journal.pone.0048142