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Candidate Human Genetic Polymorphisms and Severe Malaria in a Tanzanian Population

Human genetic background strongly influences susceptibility to malaria infection and progression to severe disease and death. Classical genetic studies identified haemoglobinopathies and erythrocyte-associated polymorphisms, as protective against severe disease. High throughput genotyping by mass sp...

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Detalles Bibliográficos
Autores principales: Manjurano, Alphaxard, Clark, Taane G., Nadjm, Behzad, Mtove, George, Wangai, Hannah, Sepulveda, Nuno, Campino, Susana G., Maxwell, Caroline, Olomi, Raimos, Rockett, Kirk R., Jeffreys, Anna, Riley, Eleanor M., Reyburn, Hugh, Drakeley, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483265/
https://www.ncbi.nlm.nih.gov/pubmed/23144702
http://dx.doi.org/10.1371/journal.pone.0047463