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Candidate Human Genetic Polymorphisms and Severe Malaria in a Tanzanian Population
Human genetic background strongly influences susceptibility to malaria infection and progression to severe disease and death. Classical genetic studies identified haemoglobinopathies and erythrocyte-associated polymorphisms, as protective against severe disease. High throughput genotyping by mass sp...
Autores principales: | Manjurano, Alphaxard, Clark, Taane G., Nadjm, Behzad, Mtove, George, Wangai, Hannah, Sepulveda, Nuno, Campino, Susana G., Maxwell, Caroline, Olomi, Raimos, Rockett, Kirk R., Jeffreys, Anna, Riley, Eleanor M., Reyburn, Hugh, Drakeley, Christopher |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483265/ https://www.ncbi.nlm.nih.gov/pubmed/23144702 http://dx.doi.org/10.1371/journal.pone.0047463 |
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