Splenic Red Pulp Macrophages Produce Type I Interferons as Early Sentinels of Malaria Infection but Are Dispensable for Control

Type I interferons (T1IFNs) are among the earliest cytokines produced during infections due to their direct regulation by innate immune signaling pathways. Reports have suggested that T1IFNs are produced during malaria infection, but little is known about the in vivo cellular origins of T1IFNs or th...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Charles C., Nelson, Christopher S., Wilson, Emily B., Hou, Baidong, DeFranco, Anthony L., DeRisi, Joseph L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483282/
https://www.ncbi.nlm.nih.gov/pubmed/23144737
http://dx.doi.org/10.1371/journal.pone.0048126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483282/
https://www.ncbi.nlm.nih.gov/pubmed/23144737
http://dx.doi.org/10.1371/journal.pone.0048126

Ejemplares similares