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Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression
Genome-wide association studies (GWASs) have identified thousands of single nucleotide polymorphisms (SNPs) associated with human traits and diseases. But because the vast majority of these SNPs are located in the noncoding regions of the genome their risk promoting mechanisms are elusive. Employing...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483423/ https://www.ncbi.nlm.nih.gov/pubmed/23001124 http://dx.doi.org/10.1038/ng.2416 |