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nFuse: Discovery of complex genomic rearrangements in cancer using high-throughput sequencing

Complex genomic rearrangements (CGRs) are emerging as a new feature of cancer genomes. CGRs are characterized by multiple genomic breakpoints and thus have the potential to simultaneously affect multiple genes, fusing some genes and interrupting other genes. Analysis of high-throughput whole-genome...

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Detalles Bibliográficos
Autores principales: McPherson, Andrew, Wu, Chunxiao, Wyatt, Alexander W., Shah, Sohrab, Collins, Colin, Sahinalp, S. Cenk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483554/
https://www.ncbi.nlm.nih.gov/pubmed/22745232
http://dx.doi.org/10.1101/gr.136572.111