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nFuse: Discovery of complex genomic rearrangements in cancer using high-throughput sequencing
Complex genomic rearrangements (CGRs) are emerging as a new feature of cancer genomes. CGRs are characterized by multiple genomic breakpoints and thus have the potential to simultaneously affect multiple genes, fusing some genes and interrupting other genes. Analysis of high-throughput whole-genome...
Autores principales: | McPherson, Andrew, Wu, Chunxiao, Wyatt, Alexander W., Shah, Sohrab, Collins, Colin, Sahinalp, S. Cenk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483554/ https://www.ncbi.nlm.nih.gov/pubmed/22745232 http://dx.doi.org/10.1101/gr.136572.111 |
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