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A miRNA-regulatory network explains how dysregulated miRNAs perturb oncogenic processes across diverse cancers

Genes regulated by the same miRNA can be discovered by virtue of their coexpression at the transcriptional level and the presence of a conserved miRNA-binding site in their 3′ UTRs. Using this principle we have integrated the three best performing and complementary algorithms into a framework for in...

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Detalles Bibliográficos
Autores principales: Plaisier, Christopher L., Pan, Min, Baliga, Nitin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483559/
https://www.ncbi.nlm.nih.gov/pubmed/22745231
http://dx.doi.org/10.1101/gr.133991.111