Targeted DNA vaccines for enhanced induction of idiotype-specific B and T cells

Background: Idiotypes (Id) are antigenic determinants localized in variable (V) regions of Ig. Id-specific T and B cells (antibodies) play a role in immunotherapy of Id(+) tumors. However, vaccine strategies that enhance Id-specific responses are needed. Methods: Id(+) single-chain fragment variable...

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Detalles Bibliográficos
Autores principales: Fredriksen, Agnete B., Sandlie, Inger, Bogen, Bjarne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483591/
https://www.ncbi.nlm.nih.gov/pubmed/23115759
http://dx.doi.org/10.3389/fonc.2012.00154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483591/
https://www.ncbi.nlm.nih.gov/pubmed/23115759
http://dx.doi.org/10.3389/fonc.2012.00154

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