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Mesenchymal stem cells from Shwachman–Diamond syndrome patients display normal functions and do not contribute to hematological defects

Shwachman–Diamond syndrome (SDS) is a rare inherited disorder characterized by bone marrow (BM) dysfunction and exocrine pancreatic insufficiency. SDS patients have an increased risk for myelodisplastic syndrome and acute myeloid leukemia. Mesenchymal stem cells (MSCs) are the key component of the h...

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Detalles Bibliográficos
Autores principales: André, V, Longoni, D, Bresolin, S, Cappuzzello, C, Dander, E, Galbiati, M, Bugarin, C, Di Meglio, A, Nicolis, E, Maserati, E, Serafini, M, Warren, A J, te Kronnie, G, Cazzaniga, G, Sainati, L, Cipolli, M, Biondi, A, D'Amico, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483621/
https://www.ncbi.nlm.nih.gov/pubmed/23064742
http://dx.doi.org/10.1038/bcj.2012.40