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Electroporation- and Mechanical Ventilation-Mediated Gene Transfer to the Lung

Our lab has previously demonstrated that cytoplasmic trafficking and subsequent nuclear entry of non-viral plasmid DNA can be significantly enhanced through the application of cyclic stretch following transfection in vitro (1,2). Here, we demonstrate that cyclic stretching of the murine lung using v...

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Detalles Bibliográficos
Autores principales: Kaufman, Christopher D., Geiger, R. Christopher, Dean, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483646/
https://www.ncbi.nlm.nih.gov/pubmed/20428212
http://dx.doi.org/10.1038/gt.2010.57