β-Catenin Does Not Confer Tumorigenicity When Introduced into Partially Transformed Human Mesenchymal Stem Cells

Although osteosarcoma is the most common primary malignant bone tumor in children and adolescents, its cell of origin and the genetic alterations are unclear. Previous studies have shown that serially introducing hTERT, SV40 large TAg, and H-Ras transforms human mesenchymal stem cells into two disti...

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Detalles Bibliográficos
Autores principales: Piperdi, Sajida, Austin-Page, Lukas, Geller, David, Ahluwalia, Manpreet, Gorlick, Sarah, Gill, Jonathan, Park, Amy, Zhang, Wendong, Li, Nan, Chung, So Hak, Gorlick, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483784/
https://www.ncbi.nlm.nih.gov/pubmed/23125530
http://dx.doi.org/10.1155/2012/164803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483784/
https://www.ncbi.nlm.nih.gov/pubmed/23125530
http://dx.doi.org/10.1155/2012/164803

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