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β-Catenin Does Not Confer Tumorigenicity When Introduced into Partially Transformed Human Mesenchymal Stem Cells
Although osteosarcoma is the most common primary malignant bone tumor in children and adolescents, its cell of origin and the genetic alterations are unclear. Previous studies have shown that serially introducing hTERT, SV40 large TAg, and H-Ras transforms human mesenchymal stem cells into two disti...
Autores principales: | Piperdi, Sajida, Austin-Page, Lukas, Geller, David, Ahluwalia, Manpreet, Gorlick, Sarah, Gill, Jonathan, Park, Amy, Zhang, Wendong, Li, Nan, Chung, So Hak, Gorlick, Richard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483784/ https://www.ncbi.nlm.nih.gov/pubmed/23125530 http://dx.doi.org/10.1155/2012/164803 |
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