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Identification of novel myeloma-specific XBP1 peptides able to generate cytotoxic T lymphocytes: A potential therapeutic application in multiple myeloma

The purpose of these studies was to identify HLA-A2(+) immunogenic peptides derived from XBP1 antigens to induce a multiple myeloma (MM)-specific immune response. Six native peptides from non-spliced XBP1 antigen and three native peptides from spliced XBP1 antigen were selected and evaluated for the...

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Detalles Bibliográficos
Autores principales: Bae, Jooeun, Carrasco, Ruben, Lee, Ann-Hwee, Tai, Yu-Tzu, Anderson, Kenneth C., Munshi, Nikhil C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483794/
https://www.ncbi.nlm.nih.gov/pubmed/21660045
http://dx.doi.org/10.1038/leu.2011.120