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Trigeminal-Rostral Ventromedial Medulla circuitry is involved in orofacial hyperalgesia contralateral to tissue injury

BACKGROUND: Our previous studies have shown that complete Freund’s adjuvant (CFA)-induced masseter inflammation and microinjection of the pro-inflammatory cytokine interleukin-1β (IL-1β) into the subnucleus interpolaris/subnucleus caudalis transition zone of the spinal trigeminal nucleus (Vi/Vc) can...

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Detalles Bibliográficos
Autores principales: Chai, Bryan, Guo, Wei, Wei, Feng, Dubner, Ronald, Ren, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484042/
https://www.ncbi.nlm.nih.gov/pubmed/23092240
http://dx.doi.org/10.1186/1744-8069-8-78