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Mechanisms of Xenogeneic Baboon Platelet Aggregation and Phagocytosis by Porcine Liver Sinusoidal Endothelial Cells

BACKGROUND: Baboons receiving xenogeneic livers from wild type and transgenic pigs survive less than 10 days. One of the major issues is the early development of profound thrombocytopenia that results in fatal hemorrhage. Histological examination of xenotransplanted livers has shown baboon platelet...

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Detalles Bibliográficos
Autores principales: Peng, Qiang, Yeh, Heidi, Wei, Lingling, Enjyoj, Keiichi, Machaidze, Zurab, Csizmad, Eva, Schuetz, Christian, Lee, Kang Mi, Deng, Shaoping, Robson, Simon C., Markmann, James, Buhler, Leo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484054/
https://www.ncbi.nlm.nih.gov/pubmed/23118867
http://dx.doi.org/10.1371/journal.pone.0047273