Loss of FGF-Dependent Mesoderm Identity and Rise of Endogenous Retinoid Signalling Determine Cessation of Body Axis Elongation

The endogenous mechanism that determines vertebrate body length is unknown but must involve loss of chordo-neural-hinge (CNH)/axial stem cells and mesoderm progenitors in the tailbud. In early embryos, Fibroblast growth factor (FGF) maintains a cell pool that progressively generates the body and dif...

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Detalles Bibliográficos
Autores principales: Olivera-Martinez, Isabel, Harada, Hidekiyo, Halley, Pamela A., Storey, Kate G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484059/
https://www.ncbi.nlm.nih.gov/pubmed/23118616
http://dx.doi.org/10.1371/journal.pbio.1001415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484059/
https://www.ncbi.nlm.nih.gov/pubmed/23118616
http://dx.doi.org/10.1371/journal.pbio.1001415

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