Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia

Cystic fibrosis (CF) is caused by the functional expression defect of the CF transmembrane conductance regulator (CFTR) chloride channel at the apical plasma membrane. Impaired bacterial clearance and hyperactive innate immune response are hallmarks of the CF lung disease, yet the existence of and m...

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Detalles Bibliográficos
Autores principales: Veit, Guido, Bossard, Florian, Goepp, Julie, Verkman, A. S., Galietta, Luis J. V., Hanrahan, John W., Lukacs, Gergely L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484098/
https://www.ncbi.nlm.nih.gov/pubmed/22973054
http://dx.doi.org/10.1091/mbc.E12-06-0424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484098/
https://www.ncbi.nlm.nih.gov/pubmed/22973054
http://dx.doi.org/10.1091/mbc.E12-06-0424

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