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Hect E3 ubiquitin ligase Tom1 controls Dia2 degradation during the cell cycle

The ubiquitin proteasome system plays a pivotal role in controlling the cell cycle. The budding yeast F-box protein Dia2 is required for genomic stability and is targeted for ubiquitin-dependent degradation in a cell cycle–dependent manner, but the identity of the ubiquitination pathway is unknown....

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Detalles Bibliográficos
Autores principales: Kim, Dong-Hwan, Koepp, Deanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484099/
https://www.ncbi.nlm.nih.gov/pubmed/22933573
http://dx.doi.org/10.1091/mbc.E12-07-0548