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The tyrosine phosphatase SHP2 regulates recovery of endothelial adherens junctions through control of β-catenin phosphorylation

Impaired endothelial barrier function results in a persistent increase in endothelial permeability and vascular leakage. Repair of a dysfunctional endothelial barrier requires controlled restoration of adherens junctions, comprising vascular endothelial (VE)-cadherin and associated β-, γ-, α-, and p...

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Detalles Bibliográficos
Autores principales: Timmerman, Ilse, Hoogenboezem, Mark, Bennett, Anton M., Geerts, Dirk, Hordijk, Peter L., van Buul, Jaap D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484100/
https://www.ncbi.nlm.nih.gov/pubmed/22956765
http://dx.doi.org/10.1091/mbc.E12-01-0038