Calcium-Activated-Calcineurin Reduces the In Vitro and In Vivo Sensitivity of Fluconazole to Candida albicans via Rta2p

Due to the emergence of drug-resistance, first-line therapy with fluconazole (FLC) increasingly resulted in clinical failure for the treatment of candidemia. Our previous studies found that in vitro RTA2 was involved in the calcineurin-mediated resistance to FLC in C. albicans. In this study, we fou...

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Detalles Bibliográficos
Autores principales: Jia, Yu, Tang, Ren-Jie, Wang, Lin, Zhang, Xiang, Wang, Ying, Jia, Xin-Ming, Jiang, Yuan-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484117/
https://www.ncbi.nlm.nih.gov/pubmed/23118995
http://dx.doi.org/10.1371/journal.pone.0048369

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484117/
https://www.ncbi.nlm.nih.gov/pubmed/23118995
http://dx.doi.org/10.1371/journal.pone.0048369

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