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Skewed Production of IL-6 and TGFβ by Cultured Salivary Gland Epithelial Cells from Patients with Sjögren's Syndrome

OBJECTIVE: To determine the cytokine production profile of cultured salivary gland epithelial (SGE) cells obtained from patients with Sjögren's syndrome (SS). METHODS: SGE cells obtained from 9 SS patients and 6 normal controls were cultured in the presence of exogenous IFNγ. Cell proliferation...

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Detalles Bibliográficos
Autores principales: Kawanami, Takafumi, Sawaki, Toshioki, Sakai, Tomoyuki, Miki, Miyuki, Iwao, Haruka, Nakajima, Akio, Nakamura, Takuji, Sato, Tomomi, Fujita, Yoshimasa, Tanaka, Masao, Masaki, Yasufumi, Fukushima, Toshihiro, Hirose, Yuko, Taniguchi, Makoto, Sugimoto, Naotoshi, Okazaki, Toshiro, Umehara, Hisanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484144/
https://www.ncbi.nlm.nih.gov/pubmed/23118848
http://dx.doi.org/10.1371/journal.pone.0045689