Cargando…

The Balance of Apoptotic and Necrotic Cell Death in Mycobacterium tuberculosis Infected Macrophages Is Not Dependent on Bacterial Virulence

BACKGROUND: An important mechanism of Mycobacterium tuberculosis pathogenesis is the ability to control cell death pathways in infected macrophages: apoptotic cell death is bactericidal, whereas necrotic cell death may facilitate bacterial dissemination and transmission. METHODS: We examine M.tuberc...

Descripción completa

Detalles Bibliográficos
Autores principales: Butler, Rachel E., Brodin, Priscille, Jang, Jichan, Jang, Mi-Seon, Robertson, Brian D., Gicquel, Brigitte, Stewart, Graham R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484146/
https://www.ncbi.nlm.nih.gov/pubmed/23118880
http://dx.doi.org/10.1371/journal.pone.0047573