DSIR: Assessing the Design of Highly Potent siRNA by Testing a Set of Cancer-Relevant Target Genes

Chemically synthesized small interfering RNA (siRNA) is a widespread molecular tool used to knock down genes in mammalian cells. However, designing potent siRNA remains challenging. Among tools predicting siRNA efficacy, very few have been validated on endogenous targets in realistic experimental co...

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Detalles Bibliográficos
Autores principales: Filhol, Odile, Ciais, Delphine, Lajaunie, Christian, Charbonnier, Peggy, Foveau, Nicolas, Vert, Jean-Philippe, Vandenbrouck, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484153/
https://www.ncbi.nlm.nih.gov/pubmed/23118925
http://dx.doi.org/10.1371/journal.pone.0048057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484153/
https://www.ncbi.nlm.nih.gov/pubmed/23118925
http://dx.doi.org/10.1371/journal.pone.0048057

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