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Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans

Despite intensive anti-hypertensive therapy there was a high incidence of renal end-points in participants of the African American Study of Kidney Disease and Hypertension (AASK) cohort. To better understand this, coding variants in the apolipoprotein L1 (APOL1) and the non-muscle myosin heavy chain...

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Detalles Bibliográficos
Autores principales: Lipkowitz, Michael S., Freedman, Barry I., Langefeld, Carl D., Comeau, Mary E., Bowden, Donald W., Kao, W.H. Linda, Astor, Brad C., Bottinger, Erwin P., Iyengar, Sudha K., Klotman, Paul E., Freedman, Richard G., Zhang, Weijia, Parekh, Rulan S., Choi, Michael J., Nelson, George W., Winkler, Cheryl A., Kopp, Jeffrey B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484228/
https://www.ncbi.nlm.nih.gov/pubmed/22832513
http://dx.doi.org/10.1038/ki.2012.263