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Unwinding of synthetic replication and recombination substrates by Srs2

The budding yeast Srs2 protein possesses 3′ to 5′ DNA helicase activity and channels untimely recombination to post-replication repair by removing Rad51 from ssDNA. However, it also promotes recombination via a synthesis-dependent strand-annealing pathway (SDSA). Furthermore, at the replication fork...

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Detalles Bibliográficos
Autores principales: Marini, Victoria, Krejci, Lumir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3484393/
https://www.ncbi.nlm.nih.gov/pubmed/22921573
http://dx.doi.org/10.1016/j.dnarep.2012.05.007